Genetics and inherited conditions

• While there remains much to learn about this disease, we know it is caused by gene mutations, or changes, that result in cells growing out of control.
• As you age, genemutations accumulate, and this is why colorectal cancer most often happens in people over age 50. In most cases, the gene mutations leading to cancer happen randomly, although they can be helped along by carcinogens, like the chemicals in cigarette smoke.
• About 25 percent of cases patients have a family history of the disease, signaling a possible condition that increases the likelihood of colorectal cancer at a younger age.

• In certain individuals, genetic mutations that increase the risk of cancer can be inherited from parents.
• Inherited genetic mutations play a role in five to ten percent of all cancer cases, as well as colorectal cancer.
• Researchers have found more than 50 hereditary cancer syndromes overall. Fortunately, a number of these inherited conditions can beidentified through genetic testing and the results can be lifesaving.

Talk to your doctor about being genetic testing. These tests:

• Can find gene mutations linked to inherited syndromes.
• Are typically conducted with either a blood or saliva draw.