Project Cure CRC
The Alliance is on a mission to end colorectal cancer. With Project Cure CRC, we’re funding research to make it happen.
Project Cure CRC addresses an urgent need
Colorectal cancer claims more than 50,000 lives annually in the U.S., with a 13% survival rate for metastatic disease. Despite rising cases in young adults, research funding lags behind, threatening to make CRC the deadliest cancer under 50 by 2030.
Our plan to find cures
We initiated Project Cure CRC to make a difference in outcomes for the millions of people affected by this disease, and we are committed to working with experts, industry, and donors to achieve that goal.
A $100 million commitment
Project Cure CRC is making available tens of millions of dollars to innovators whose work aims to expedite colorectal cancer research to a curable science.
Innovation is in progress
Project Cure CRC has already invested millions of dollars into promising high-risk/high-reward research.
Seeking visionaries
Ending colorectal cancer will take broad collaboration. The Alliance seeks supporters and researchers to advance Project Cure CRC.
Project CRC Consortium Members
Leadership Advisory Council
Advisory Subcommittee Members
Additional Consortium Members
Up Next
The breakthrough fundTop resources
FDA Clears Way for Colorectal Cancer Clinical Trial Led by Dr. Christopher Lieu
The U.S. Food and Drug Administration has given researchers at the University of Colorado Anschutz Medical Campus permission to begin a clinical trial of CAR T-cell therapy for people with advanced colorectal cancer who have already tried the standard treatments without lasting success.
Alliance and GCAR Announce Collaboration to Advance a Groundbreaking Adaptive Clinical Trial Platform for CRC: KLEOS
A first-of-its-kind trial platform in the colorectal cancer space, Project Cure CRC’s KLEOS is being driven by the Colorectal Cancer Alliance, the leading nonprofit dedicated to ending the disease, in collaboration with GCAR, a pioneer in the design and implementation of innovative clinical trials.
Alliance Presents Poster Sessions & Speaks at Symposium During AACR Annual Meeting
The Colorectal Cancer Alliance will present three poster sessions and deliver an oral presentation at the American Association for Cancer Research Annual Meeting 2026.