Join the movement
We can change the trajectory of colorectal cancer together.

Seeking collaborative researchers
Project Cure CRC is a multi-faceted effort combining innovative research and cutting-edge venture philanthropy. Ending colorectal cancer will take all of us, in collaboration, driving urgently toward cures.
Direct funding
Project Cure CRC’s fund for breakthoughs supports science from a wide variety of researchers.
Young Investigator Accelerator Award
Supports early-career faculty with innovative ideas in CRC research, providing up to $200,000 over two years for original preclinical, translational, or early clinical projects.
Senior Investigator Accelerator Award
Funds transformative research to advance CRC therapies, offering up to $500,000 over two years for senior investigators proposing localized or metastatic CRC projects.
Pilot Accelerator Award
Encourages high-risk, high-reward CRC research with clear hypotheses, providing up to $200,000 over two years to establish proof-of-concept.
Team Science Accelerator Award
Supports collaborative, multidisciplinary CRC research teams with up to $500,000 over two years to drive curative science and innovation.
Opportunistic Award
The Opportunistic Award is not being offered as of October 1, 2025. Funding opportunities for small biotech companies are being included in a Request for Proposals for K-SPY, Project Cure CRC’s adaptive clinical trial platform with release anticipated by mid-November 2025. The Alliance encourages small companies focused on new therapies and technologies for colorectal cancer to review the forthcoming RFP and submit proposals to accelerate new cures for CRC patients.
Innovators wanted
Project Cure CRC prioritizes high-risk/high-reward proposals that fast-track research toward curative solutions, with a strong preference for collaborative and public-private partnerships.
Sponsors
Up Next
Funded researchTop resources

Project Cure CRC Continues to Fuel Urgently Needed Research Funding
The Alliance's Project Cure CRC announces $1.3 million in new research grants — bringing total funding to nearly $12 million — to drive breakthroughs in colorectal cancer care and address critical research gaps.

2025 ASCO update: Six big studies
The 2025 ASCO Annual Meeting featured several important studies that could change how colorectal cancer is treated, including a pivotal study for BRAF V600E patients.