Join the movement
We can change the trajectory of colorectal cancer together.
Research program update
The Alliance Research Grant Program (RFP) has been temporarily suspended to allow our resources to focus on establishing the adaptive clinical trial platform under Project Cure CRC. Future research funding will be dependent on available resources and alignment with this strategic priority.
We anticipate reopening the RFP later in 2026; however, a specific timeline has not yet been determined. Updates will be shared as they become available.
If investigators have concepts or ideas that may align with the adaptive clinical trial platform, we welcome you to reach out to research@ccalliance.org so we can stay connected as this work evolves.
When the program reopens, announcements will be posted. We appreciate the research community’s continued partnership and commitment to advancing colorectal cancer research.
Direct funding
Project Cure CRC’s fund for breakthoughs supports science from a wide variety of researchers.
Young Investigator Accelerator Award
Supports early-career faculty with innovative ideas in CRC research, providing up to $200,000 over two years for original preclinical, translational, or early clinical projects.
Senior Investigator Accelerator Award
Funds transformative research to advance CRC therapies, offering up to $500,000 over two years for senior investigators proposing localized or metastatic CRC projects.
Pilot Accelerator Award
Encourages high-risk, high-reward CRC research with clear hypotheses, providing up to $200,000 over two years to establish proof-of-concept.
Team Science Accelerator Award
Supports collaborative, multidisciplinary CRC research teams with up to $500,000 over two years to drive curative science and innovation.
Opportunistic Award
The Opportunistic Award is not being offered as of October 1, 2025. Funding opportunities for small biotech companies are being included in a Request for Proposals for Project Cure CRC’s adaptive clinical trial platform with release anticipated by mid-November 2025. The Alliance encourages small companies focused on new therapies and technologies for colorectal cancer to review the forthcoming RFP and submit proposals to accelerate new cures for CRC patients.
Sponsors
Up Next
Funded researchTop resources
Bringing biomarker testing within reach: CLEAR for CRC to empower patients from day one
Biomarker testing can guide colorectal cancer treatment and improve outcomes. Learn how CLEAR for CRC is helping patients access this critical tool.
Project Cure CRC researcher seeks next big breakthrough
Meet Project Cure CRC researcher Kevin Van der Jeught, whose mRNA-based immunotherapy research aims to unlock new treatments for colorectal cancer patients.
Alliance Wins 2025 Amazon Web Services Imagine Grant
The grant will support the Alliance’s Project Cure CRC initiative to connect and analyze real-world patient and clinical data across institutions, enabling personalized treatment pathways, accelerating innovation and establishing a learning cycle that translates research insights back to patient care.