Research funded by Project Cure CRC

    Innovation is in progress.

    Funded research

    Raghu Kalluri, MD, PhD
    Therapy for MSS disease

    Raghu Kalluri, MD, PhD

    Dr. Kalluri of MD Anderson Cancer Center aims to develop urgently needed therapeutic options for the 96% of colorectal cancer patients with microsatellite stable (MSS) disease.

    H. Charles Manning, PhD
    Theranostics for BRAF mutations

    H. Charles Manning, PhD

    H. Charles Manning, PhD, a professor at MD Anderson Cancer Center, will lead a collaborative effort to discover the first theranostic pair for imaging and therapy for patients with CRC. 

    Peter Lee, MD
    Immunotherapy for MSS disease

    Peter Lee, MD

    Dr. Peter Lee of City of Hope will pursue a novel combination immunotherapy to treat metastatic MSS colorectal cancer, which does not respond well to current treatments.

    Kevin Van der Jeught, PhD
    mRNA vaccine for CRC

    Kevin Van der Jeught, PhD

    Kevin Van Der Jeught, PhD, of the University of Miami, seeks to improve intratumoral mRNA vaccination strategies by targeting immune checkpoints to enhance anti-tumor immune responses.

    Ekaterina Dadachova
    Targeted radioimmunotherapy

    Ekaterina Dadachova, PhD

    Ekaterina Dadachova, PhD, of The University of Saskatchewan will investigate combining targeted radiation with immunotherapies for a novel and synergistic approach to treat advanced colorectal cancer, improving clinical outcomes.

    Yekaterina Y. Zaytseva
    New Drug Combinations for BRAF

    Yekaterina Y. Zaytseva, PhD

    Yekaterina Y. Zaytseva, PhD, of the University of Kentucky, will investigate new drug combinations to kill CRC cells with a BRAF mutation. These cells currently have a low response rate to existing treatments. 

    Dr. Ashiq Masood
    Investigating a New Protein

    Ashiq Masood, MD

    Dr. Masood of Indiana University is studying ProAgio, a new protein that targets cells aiding cancer's survival. This approach could improve therapies for tough-to-treat tumors.

    Dr. Caterina Suelzu
    Body Fat & CRC

    Caterina Suelzu, PhD

    Dr. Suelzu of Anglia Ruskin University will investigate how fat tissue impacts the growth and spread of colorectal cancer, especially in people with obesity. 

    Dr. Julia Carnevale
    Innovating with CRISPR

    Julia Carnevale, MD

    Dr. Carnevale of UCSF will use cutting-edge technology to target multiple genes at once, seeking to uncover weaknesses in cancer cells and boost the body’s immune response. 

    Dr. David Robbins
    Stopping the Spread

    David Robbins, PhD

    Dr. Robbins of Georgetown University aims to target and stop the circulating tumor cells responsible for forming metastatic tumors. Success could improve mCRC survival rates. 

    By the numbers: Project Cure CRC

    $7M

    in funding allocated 

    19

    projects supported

    $100M

    funding goal

    Join us

    Project Cure CRC seeks research proposals from early-career investigators, senior investigators, teams, startup companies, and others. We prioritize collaboration toward curative science. 

    DOWNLOAD RFP

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