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A smiling family of four, including John E., poses outdoors with a saddled brown horse at a mountain ranch, with pine-covered hills, fencing, and ski lift cables visible in the background on a sunny day.

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John E.: Biomarker testing uncovered a pivotal treatment option

After a grim prognosis, biomarker testing revealed a targeted treatment option for John E. Learn how knowing your biomarkers can change what’s possible.

Jan 14, 2026

Three photos showing Kate Shin and her mother, Lynn, at different stages of their lives. Left: Lynn stands with young Kate in a blue dress. Center: Lynn smiles beside her husband on a couch. Right: Kate and Lynn sit close together at a dinner table, smiling warmly.

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"Clinical trials gave us time": A daughter’s tribute to her mother’s courage

When Kate Shin’s mother faced rectal cancer, clinical trials gave them precious time together. Now, Kate shares her story to encourage access to screening and innovative care, including clinical trials.

Oct 28, 2025

The main corridor at the 2025 ASCO Annual Meeting

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2025 ASCO update: Six big studies

The 2025 ASCO Annual Meeting featured several important studies that could change how colorectal cancer is treated, including a pivotal study for BRAF V600E patients.

Jun 24, 2025

Blog

NIH: Combination immunotherapy shrank GI cancers

A new kind of tumor infiltrating lymphocyte (TIL) therapy improved the treatment’s effectiveness in patients with metastatic GI cancers.

Apr 1, 2025

A photograph of Lexie in a chemotherapy chair.

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Lexie Haglund: Beating stage IV CRC

Discover how knowing her G12C biomarker guided Lexie’s stage IV colorectal cancer treatment — from a shock diagnosis to HIPEC surgery — and why screening, research, and self-advocacy matter.

Feb 26, 2025

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HAI liver pump for mCRC offers second chances

Discover how Hope overcame stage IV colorectal cancer with an innovative HAI liver pump, staying active and proving that second chances are possible.

Jan 27, 2025

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Michelle Cappel: Biomarker testing extends life

Michelle Cappel owes a lot to colorectal cancer biomarker testing — seven years of life and counting.

Jan 8, 2024

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Don Shippey: from stage IV to six years cancer-free after receiving HAI pump

Don Shippey was 55 years old in 2016 when he decided he’d been putting off his colonoscopy long enough.

Nov 15, 2023

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FDA approves FRUZAQLA for previously treated mCRC

Takeda has announced U.S. Food and Drug Administration (FDA) approval of FRUZAQLA (fruquintinib), an oral targeted therapy for adults with metastatic colorectal cancer (mCRC) who have been previously treated with fluoropyrimidine-, oxaliplatin-, and irinotecan-based chemotherapy, an anti-VEGF therapy, and, if RAS wild-type and medically appropriate, an anti-EGFR therapy.

Nov 9, 2023

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Why the doctors chose robotic-assisted surgery

In the case of Dr. Paul O'Rourke – a 39-year-old, stage I rectal cancer survivor, and physician at Johns Hopkins – robotic-assisted surgery (RAS) was the surgical option he was fortunate he had.

Aug 17, 2023

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Clinical trial to evaluate onvansertib as first-line mCRC treatment

People with RAS-mutated metastatic colorectal cancer (mCRC) have seen little progress in first-line treatment options over the past two decades, but that could soon change for thousands of new patients, according to a press release from Cardiff Oncology.

Aug 16, 2023

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Lillian Abreu: Learning about follow-up treatment as a survivor

Lillian Abreu was thirty years old and five months pregnant when she found out she had stage I colon cancer. Thankfully, she was able to immediately undergo a right hemicolectomy without further complication to her or her baby.

Aug 7, 2023

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FDA approves lonsurf in combination with bevacizumab for metastatic colorectal cancer patients

Taiho Oncology and Taiho Pharmaceutical have announced U.S. Food and Drug Administration (FDA) approval of Lonsurf alone or in combination with bevacizumab for the treatment of adult patients with metastatic colorectal cancer (mCRC) who have undergone two prior regimens of treatment.

Aug 3, 2023

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Treatment for KRAS G12C-mutated metastatic CRC approved by FDA

The U.S. Food and Drug Administration has approved sotorasib in combination with panitumumab for the treatment of adult patients with KRAS G12C-mutated metastatic colorectal cancer.

Jan 17, 2025

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Watch session videos from AllyCon 2024

Watch videos of two major general sessions from AllyCon 2024, the Alliance's patient support conference, which took place in Miami Beach in December.

Jan 8, 2025

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Krazati approved for previously treated KRASG12C colorectal cancer

The treatment option is for patients with KRASG12C-mutated locally advanced or metastatic colorectal cancer (CRC) who have received prior treatment with fluoropyrimidine-, oxaliplatin-, and irinotecan-based chemotherapy.

Jun 25, 2024

Christy Williams, a mom and colorectal cancer survivor, plays a table-top game with her family.

Blog

Christy Williams: Biomarker testing leads to successful treatment

Statistics suggested that Christy’s odds of survival were grim, so she leaned into her faith and kept a positive outlook. She tried to control what she could. And, critically, she received biomarker testing.

Apr 21, 2024