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    Colorectal Cancer Alliance
      • The basics: what is colorectal cancer?
        • Colorectal cancer symptoms
        • Facts and statistics
        • Stages of colorectal cancer
        • Health equity
        • Glossary
        male patient with doctor in office
        What to know
        Knowing your biomarker status informs the most effective treatment plan
      • Screening & prevention: why, when, how?
        • Get screened at 45
        • How to talk to your doctor about screening
        • Colonoscopy prep tips
        • Screening methods
        • Prevention
        two people looking at phone together
        Get Screened
        Take our free screening quiz for personalized recommendations
      • Treatment: what are your options?
      • For you
        • Patients
        • Survivors
        • Caregivers
        • Newly diagnosed
        Types of Treatment
        • Surgery
        • Chemo, radiation, and other therapies
        • Clinical trials
        • Why biomarkers matter
        • Colostomy and ileostomy
        • Side effects
        Latina woman with male doctor
        RESOURCES FOR YOU
        10 questions to ask your doctor when newly diagnosed
      • Resources & Support
      • Resources
        • BlueHQ patient support hub
        • Live navigator helpline
        • Financial assistance
        • Living well with colorectal cancer
        • Palliative care
        • Hospice
        • Resource library
        Community Support
        • Online communities
        • Buddy Program
        • Young-onset support
        • Stories of hope
        • Community chat
        Dressy couple posing for selfie
        YOUR PATIENT PORTAL
        Personalized resources are ready for you on BlueHQ
      • Research: investments and influence to cure CRC
        • Need for research innovation
        • Plan to cure CRC
        • Apply for a research grant
        • Research funded by Project Cure CRC
        Project Cure Summit audience 2024
        Project Cure CRC
        Learn about our effort to fund expedited and novel cancer research
      • Get involved: help us end colorectal cancer
      • Events
        • Walk to End Colon Cancer
        • Attend a Blue Hope Bash
        • Create your own event
        • View all events
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        • Partner with us
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    Colorectal cancer resource library

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    How Signatera™ Recurrence Monitoring Helps One Patient Sleep Better
    Blog

    How Signatera recurrence monitoring helps one patient sleep better

    Provided by Natera, Signatera is a test to help reveal if cancer may be left in the body, identify recurrence earlier, and potentially inform treatment decisions.

    Oct 24, 2022
    After a Stage IV Diagnosis During Pregnancy, Biomarkers Provide Next Steps
    Blog

    After a stage IV diagnosis during pregnancy, biomarkers provide next steps

    Biomarker testing led to changing Alyssa’s treatment plan, one with a more effective combination of therapies that started to shrink her tumor and allowed her to schedule an upcoming surgery.

    May 5, 2022
    Shannon Morock: Lynch Syndrome Diagnosis a Gift of Knowledge
    Blog

    Shannon Morock: Lynch syndrome diagnosis a gift of knowledge

    After several months of bloody stools and constipation, Ally to Ally moderator Shannon Morock knew something wasn’t quite right with her body. Testing revealed cancer — and an important genetic condition. 

    Sep 6, 2020
    Yarnell Johnson: Lynch Syndrome as a Stepping Stone
    Blog

    Yarnell Johnson: Lynch syndrome as a stepping stone

    Up to 5% of all colon cancers arise from inherited syndromes, including Lynch syndrome.

    Jun 14, 2020
    Riley Castro: Armed with knowledge about genetics
    Blog

    Riley Castro: Armed with knowledge about genetics

    At 24 years old, RIley Castro found herself aboard a helicopter, speeding above the Texas plains.

    Jun 15, 2018
    For you and your family: Genetic risk and colorectal cancer
    Blog

    For you and your family: Genetic risk and colorectal cancer

    In 25 percent of colorectal cancer cases, patients have a family history of the disease, signaling a possible genetic condition that causes mutations and increases the likelihood of colorectal cancer at a younger age.

    May 8, 2018
    Blog

    Lynch syndrome: Common questions and answers

    Lynch syndrome runs in families from one generation to the next and leads to the most common inherited form of colorectal cancer, also called hereditary non-polyposis colorectal cancer (HNPCC).

    Mar 27, 2020
    Jeff Dincher: Biomarker Testing Prevents Lynch Syndrome in His Children
    Blog

    Jeff Dincher: Biomarker testing prevents Lynch syndrome in his children

    While many cancer patients get biomarker testing at diagnosis to explore treatment options, it can also help years after treatment and in unexpected ways.

    Jul 8, 2023
    Mirati to Begin Clinical Trials of Treatment for KRASG12D Colorectal Cancer
    Blog

    Mirati to begin clinical trials of treatment for KRASG12D colorectal cancer

    MRTX1133 is a potential first-in-class oral treatment for patients with the KRASG12D colorectal cancer mutation.

    Jan 25, 2023
    Study: Signatera Can Help Predict Recurrence After Colorectal Cancer Surgery
    Blog

    Study: Signatera can help predict recurrence after colorectal cancer surgery

    This information can help oncologists predict who is likely to benefit from chemotherapy after surgery, which is called adjuvant chemotherapy.

    Jan 24, 2023
    First FDA-Approved Treatment for HER2-Positive Colorectal Cancer
    Blog

    First FDA-approved treatment for HER2-positive colorectal cancer

    “Historically, patients with HER2-positive metastatic colorectal cancer who have progressed following frontline therapy have had poor outcomes,” said John Strickler, M.D. and lead investigator of the MOUNTAINEER trial. “The FDA approval of a chemotherapy-free combination regimen that specifically targets HER2 is great news for these patients.”

    Jan 20, 2023
    Alliance Pushes for Medicare Coverage of Genetic Counseling
    Blog

    Alliance pushes for Medicare coverage of genetic counseling

    There is bi-partisan legislation pending in Congress that would fix this and help modernize Medicare and catch up with the advances in genetics and genomic medicine.

    Nov 18, 2022
    Michelle Cappel: Biomarker testing extends life
    Blog

    Michelle Cappel: Biomarker testing extends life

    Michelle Cappel owes a lot to colorectal cancer biomarker testing — seven years of life and counting.

    Jan 8, 2024
    Not All States Mandate Biomarker Testing Coverage
    Blog

    Not all states mandate biomarker testing coverage

    While Congress has yet to bring Medicare coverage fully up to speed with advances in biomarker testing, many states are acting.

    Dec 17, 2023
    Janice Johnson: Get Informed & Advocate for Yourself
    Blog

    Janice Johnson: get informed and advocate for yourself

    When Janice Johnson started experiencing sudden GI symptoms at the age of 48, a cancer diagnosis was the last thing she expected. In fact, it was difficult for her to even get a colonoscopy in the first place, being that the recommended screening age was 50 at the time (2016).

    Nov 5, 2023
    Christy Williams, a mom and colorectal cancer survivor, plays a table-top game with her family.
    Blog

    Christy Williams: Biomarker testing leads to successful treatment

    Statistics suggested that Christy’s odds of survival were grim, so she leaned into her faith and kept a positive outlook. She tried to control what she could. And, critically, she received biomarker testing.

    Apr 21, 2024
    A sign at the BMS headquarters
    Blog

    Krazati approved for previously treated KRASG12C colorectal cancer

    The treatment option is for patients with KRASG12C-mutated locally advanced or metastatic colorectal cancer (CRC) who have received prior treatment with fluoropyrimidine-, oxaliplatin-, and irinotecan-based chemotherapy.

    Jun 25, 2024
    A photograph of Lexie in a chemotherapy chair.
    Blog

    Lexie Haglund: Beating stage IV CRC

    Discover how knowing her G12C biomarker guided Lexie’s stage IV colorectal cancer treatment — from a shock diagnosis to HIPEC surgery — and why screening, research, and self-advocacy matter.

    Feb 26, 2025
    Blog

    FDA approves new treatment for metastatic CRC with BRAF mutation

    The U.S. Food and Drug Administration has approved encorafenib (marketed as BRAFTOVI) in combination with cetuximab (marketed as ERBITUX) as a second-line therapy for the treatment of adult patients with metastatic colorectal cancer with a BRAFV600E mutation.

    Apr 22, 2020
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