Screen Smart
The Colorectal Cancer Alliance's Screen Smart initiative empowers stakeholders with data-driven insights for smarter colorectal cancer screening decisions.

Navigating a complex landscape
The Alliance launched Screen Smart in 2024, serving as a convener and thought leader to provide critical data and insights on data, access, and adherence in colorectal cancer screening.
Our goals
To address these challenges, the Colorectal Cancer Alliance’s Screen Smart initiative focuses on three core goals:

Share insights
Clarify the screening landscape by sharing data-driven insights on current and emerging screening modalities.

Address barriers
Improve access and adoption by identifying and addressing barriers to equitable implementation through expert panels and policy discussions.

Support users
Enhance data-driven decision-making by disseminating timely information on test approvals, performance metrics, and pipeline developments to support providers and patients.
The current situation
Over the past several decades, research in colorectal cancer prevention and early detection has led to the development of a growing number of screening modalities. In recent years, innovation in this space has accelerated rapidly, introducing new technologies and approaches. However, this progress has also created a complex and often confusing landscape for both healthcare professionals and patients. The proliferation of options — combined with limited head-to-head comparisons and

inconsistent data — has made it more difficult to make informed decisions about screening. Additionally, new barriers have emerged around equitable access and adoption of the latest screening tests.
Our progress
In 2024, the Colorectal Cancer Alliance hosted a discussion during Digestive Disease Week to address colorectal cancer screening tests. They collected data and developed a framework for evaluating various screening options, followed by discussions with medical directors from screening test companies. The 2025 Screen Smart discussion emphasized emerging technologies, adherence strategies based on modeling studies, and anticipated challenges related to access in screening.
Looking ahead
The 2025 Screen Smart discussion culminated in a forthcoming paper drawing upon insights from 2024, as well. The Alliance will leverage these findings to develop plain-language tools for patients and to create comprehensive educational resources for healthcare providers. Through these efforts, the Alliance aims to generate actionable insights that empower healthcare providers with cutting-edge knowledge and equip patient advocates with the tools they need to drive improvements in screening access, adherence, and outcomes.

Save the Date: 2026 Screen Smart Event
📅 May 2026
📍 Chicago
🕠 More details forthcoming
🔹 Email screensmart@ccalliance.org to express interest in attending
2025 Screen Smart Dinner Advisory Committee
The advisory committee is comprised of dedicated individuals who are passionate about savings lives by increasing colorectal cancer screening rates.
Michael Sapienza
Chief Executive Officer, Colorectal Cancer Alliance
Djenaba Joseph, MD, MPH
CAPT., U.S. Public Service Centers for Disease Control
Richard Wender, MD
Professor and Chair Family Medicine and Community Health, University of Pennsylvania
Pam G. Traxel
Senior Vice President, ACS CAN
Lee Dranikoff, BA, MA, JD
Patient Representative, Chair of the Board of the Colorectal Cancer Alliance, Founder of Practical Strategy